Direct amidation of non-activated phenylacetic acid and benzylamine derivatives catalysed by NiCl 2
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چکیده
منابع مشابه
Direct amidation of non-activated phenylacetic acid and benzylamine derivatives catalysed by NiCl2
This paper describes an eco-friendly and efficient direct amidation of benzylamine and phenylacetic acid derivatives in the presence of 10 mol% NiCl2 as catalyst without any drying agent. For the different phenylacetic acid and benzylamine derivatives, the direct catalysed amidation gave moderate-to-excellent yields in toluene. The steric and electronic effects of substituent groups on the phen...
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Centre for Sustainable Chemical Process University, Science Site, South Road, Durha durham.ac.uk Department of Chemistry, University Coll WC1H 0AJ, UK Department of Chemistry, Durham Univer DH1 3LE, UK Department of Chemistry, Imperial Colle London, SW7 2AZ, UK † Electronic supplementary information spectra, computational data and ES 1551614–1551624 and 1563948–1563950. CIF or other electronic ...
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Reversed-phase preparative HPLC analysis of the methanol extract of the seeds of Ilex aquifolium afforded two antioxidant phenylacetic acid derivatives, 2,4-dihydroxyphenylacetic acid (1) and 2,4-dihydroxyphenylacetic acid methyl ester (2). The structures were determined by spectroscopic methods. In the DPPH assay for antioxidant activity, the IC(50) values of 1 and 2 were 1.50 x 10(-3) and 2.5...
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ژورنال
عنوان ژورنال: Royal Society Open Science
سال: 2018
ISSN: 2054-5703
DOI: 10.1098/rsos.171870